The Skull Base Anatomy Laboratory at the University of Chicago is dedicated to advancing the art and science of skull base surgery through rigorous anatomical research, surgical innovation, and hands-on education. Our mission is to bridge the gap between detailed anatomical understanding and real-world surgical application to improve outcomes for patients with complex cranial base disorders.

Core Areas of Focus

Endoscopic and Open Skull Base Approaches

Our lab conducts high-resolution anatomical studies that support the development and refinement of both endoscopic and open approaches to the skull base. We aim to enhance the precision, safety, and effectiveness of surgeries involving the anterior, middle, and posterior cranial fossae.

Comparative Surgical Anatomy

By analyzing the anatomical advantages and limitations of traditional versus emerging surgical corridors, we support data-driven decision-making in the operating room. This includes work on extended endonasal approaches, transorbital corridors, and lateral skull base pathways.

Innovation in Surgical Technique

Our team is actively involved in the design and validation of novel approaches to access deep-seated lesions. This includes translational work from cadaveric dissection to operative technique development, emphasizing minimally invasive strategies whenever feasible.

White Matter and Cranial Nerve Dissection

We study white matter pathways and cranial nerve anatomy using both microdissection and advanced imaging techniques. These efforts support safer resection of intra-axial tumors and optimize neuromonitoring and imaging-guided interventions.

Education and Training

The Skull Base Anatomy Lab also serves as a training ground for medical students, residents, and fellows. Through structured dissection courses and one-on-one mentorship, we aim to develop technical excellence, spatial understanding, and surgical judgment in the next generation of neurosurgeons and skull base specialists.