Polster Lab

Congrats Roberto

Congrats Roberto

Our fellow has matched into neurosurgery, and most importantly, here at UChicago! Roberto’s training in clinical medicine and research portfolio set him apart, and he is well-positioned to have a successful residency. Looking forward to watching his career evolve.

Hello world!

Hello world!

Dr. Polster visited the Shanghai Blue Cross Brain Hospital and exchanged education topics and ideas on the treatment of complex neurosurgical...
Safadi Program Exapands to Study Gut-Brain interactions in TBI

Safadi Program Exapands to Study Gut-Brain interactions in TBI

Sean Polster, MD and Orlando DeLeon, PhD

In collaboration with the Departments of Neurology (Neuro-Critical Care), Medicine (Gastroenterology), and The Duchossois Family Institute

“The Role of the Gut Microbiome in Traumatic Brain Injury and Blood-Brain Barrier Integrity”

The brain-gut-axis has emerged as a powerful modulator of the neurovascular unit and the blood-brain barrier, with preliminary data suggesting it as a possible point of modification influencing outcomes in traumatic brain injury. Our study seeks to characterize microbiome and metabolic alterations in traumatic brain injury, to identify potential biomarkers and novel therapeutic strategies.

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