Neurosurgeon
Dr. Sean Polster, MD

At the University of Chicago Medicine, our Department of Neurosurgery is dedicated to providing exceptional care for patients facing complex neurological conditions. Our team of internationally recognized neurosurgeons specializes in a comprehensive range of services, including:
-
Brain Tumors: Advanced surgical techniques for benign and malignant tumors.
-
Spinal Disorders: Minimally invasive and traditional surgeries for spinal conditions.
-
Cerebrovascular Diseases: Expertise in treating aneurysms, arteriovenous malformations, and stroke.
-
Epilepsy Surgery: Innovative approaches for seizure control.
-
Pediatric Neurosurgery: Specialized care for neurological conditions in children.
Our approach is rooted in:
-
Multidisciplinary Collaboration: Working closely with specialists across disciplines to ensure comprehensive care.
-
Cutting-Edge Research: Engaging in groundbreaking research to bring the latest advancements to our patients.
-
Patient-Centered Care: Prioritizing the individual needs and values of each patient.
For Referring Physicians
We value our partnerships with referring physicians and are committed to:
-
Timely Consultations: Ensuring prompt scheduling of patient evaluations.
-
Collaborative Care: Maintaining open communication throughout the patient’s treatment journey.
-
Continuity of Care: Providing comprehensive reports and updates to support ongoing patient management.
Contact Us
To refer a patient or schedule a consultation:
-
Phone: (773) 702-2123
-
Address: 5841 S. Maryland Avenue, MC3026, Chicago, IL 60637
-
Online: Schedule an Appointment
Experience the excellence of neurosurgical care at the University of Chicago Medicine.
Latest Series: In The Moment

The University of Chicago’s Department of Neurosurgery offers world-class care grounded in innovation, precision, and compassion. Our team specializes in treating the most complex brain, spine, and neurovascular conditions using advanced surgical techniques and state-of-the-art technology—including intraoperative imaging, endoscopy, and minimally invasive approaches. We collaborate closely with referring physicians to ensure seamless, patient-centered care, from diagnosis through recovery. With a strong foundation in academic medicine and a commitment to research, we bring the latest therapies to the bedside—offering patients access to clinical trials and novel treatments not widely available elsewhere.

The Forefront
Cover article of JNS (Journal of Neurosurgery)
Our team published a state-of-the-art review highlighting the latest advances in the understanding, diagnosis, and management of cavernous angiomas—aimed at guiding both clinical care and future research.
Cover article of the Red Journal
Building on the progress of the MISTIE Trial, our team has identified key factors in ICH intervention that impact patient outcomes and established the field’s benchmark for hematoma volume reduction
Cover article of Blood
The UChicago Neurovascular team along with collaborators discover key findings related to endothelial dysfunction.
Collaboration
Grand Rounds and Coffee with our neurovascular colleagues spark vibrant discussions about the future of neurosurgery. Monthly Kluver Visiting Professor Lectures place UChicago at the center of neuroscience advancement, offering a space for surgeons and scientists to dive deep into pressing challenges and share lessons from clinical and research experience.
Why Choose Dr. Sean Polster
Patients and referring physicians choose Dr. Polster for his unique combination of surgical precision, scientific innovation, and deeply personalized care. A fellowship-trained cerebrovascular and skull base neurosurgeon at the University of Chicago, Dr. Polster is known for tackling complex brain conditions with minimally invasive techniques and cutting-edge technologies. He is also certified in gamma-knife radiosurgery and other non-invasive treatment options. He is a leader in translating research into real-world therapies, particularly in the areas of brain tumors and vascular disease. Dr. Polster takes time to understand each patient’s needs, working collaboratively with families and multidisciplinary teams to ensure thoughtful, individualized treatment plans. Whether you are facing a challenging diagnosis or seeking a second opinion, Dr. Polster is committed to delivering exceptional outcomes with empathy and integrity.
